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Advantages of Novopower
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STEPS IN CONVENTIONAL
WET GRANULATION
STEPS WITH OTHER DIRECT
COMPRESSION EXCIPIENTS
STEPS WITH NOVOPOWER
     Sifting
 
     Dry Mixing      
 
     Granulation
 
     Wet Screening
 
     Fluid Bed Drying
 
     Dry Screening
 
     Lubrication
 
     Compression

     DC Grade Lactose / MCC
 
     Drug
 
      Dry Binder
 
      Disintegrating Agent 
      (Dispersible Formulation) /
      SR Agent (Sustained Release
      Formulation)
 
      Lubricants
 
      Dry Mixing
 
      Compression
     
      DC/SR/DT/SP
 
      Drug
 
      Dry Mixing
 
      Compression
 
ADVANTAGES OF NOVOPOWER OVER CONVENTIONAL PROCESS :
  • No granulation process
  • Reduced operation time per batch
  • Reduced manpower costs
  • Higher yield than conventional granulation
  • Energy saving in terms of drying and other granulation steps
  • Reduced chances of contamination
  • Moisture and heat-free processing hence enhance drug stability
  • Elimination of hazardous steps (non aqueous granulation)
  • It saves time and money on testing of different excipients and its inventory
  • Particle size uniformity
  • The chances of batch-to-batch variation are negligible because the unit operations required for manufacturing processes are fewer
 
ADVANTAGES OF NOVOPOWER OVER D.C. GRADE EXCIPIENTS :
  • Customized formulations to suit API
  • No need of other excipients & lubricants (Single inventory)
  • Better flow-ability
  • Better hardness & low friability
  • Economical
 
Value Addition :
The Customer Service Laboratory is well equipped with all the ultra modern machineries & instruments in the factory to offer services from design & development stage till stability studies as per ICH guidelines for various tabletting processes. We emphasis on the full flagged development to customize Sustained Released formulation for SR tablets that achieved desired released profile. 

Limitation of Direct Compression
 : 
The main limitation of direct compression is it cannot be used for all drug substances. The technique depends on the major components of the formulation having appropriate flow and compaction properties. While it is possible to modify the properties of drug substances by particle engineering, this is usually outside the scope of the formulator and the formulation must be designed to accommodate the limitations imposed by the drug substance. For low dose drugs, it is usually possible to overcome such limitations through careful selection of excipients. But there will be a dose level at which it becomes impractical to produce a tablet of acceptable size.
 
 
 
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